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Induction of the Wnt Antagonist Dickkopf-1 Is Involved in Stress-Induced Hippocampal Damage

The identification of mechanisms that mediate stress-induced hippocampal damage may shed new light into the pathophysiology of depressive disorders and provide new targets for therapeutic intervention. We focused on the secreted glycoprotein Dickkopf-1 (Dkk-1), an inhibitor of the canonical Wnt path...

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Detalles Bibliográficos
Autores principales: Matrisciano, Francesco, Busceti, Carla L., Bucci, Domenico, Orlando, Rosamaria, Caruso, Alessandra, Molinaro, Gemma, Cappuccio, Irene, Riozzi, Barbara, Gradini, Roberto, Motolese, Marta, Caraci, Filippo, Copani, Agata, Scaccianoce, Sergio, Melchiorri, Daniela, Bruno, Valeria, Battaglia, Giuseppe, Nicoletti, Ferdinando
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029367/
https://www.ncbi.nlm.nih.gov/pubmed/21304589
http://dx.doi.org/10.1371/journal.pone.0016447