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MicroRNA-126 Inhibits SOX2 Expression and Contributes to Gastric Carcinogenesis

BACKGROUND: SRY (sex-determining region Y)-box 2 (SOX2) is a crucial transcription factor for the maintenance of embryonic stem cell pluripotency and the determination of cell fate. Previously, we demonstrated that SOX2 plays important roles in growth inhibition through cell cycle arrest and apoptos...

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Detalles Bibliográficos
Autores principales: Otsubo, Takeshi, Akiyama, Yoshimitsu, Hashimoto, Yutaka, Shimada, Shu, Goto, Kentaro, Yuasa, Yasuhito
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029394/
https://www.ncbi.nlm.nih.gov/pubmed/21304604
http://dx.doi.org/10.1371/journal.pone.0016617