Targeting Toll-like receptor 7/8 enhances uptake of apoptotic leukemic cells by monocyte-derived dendritic cells but interferes with subsequent cytokine-induced maturation

Therapeutic vaccination with dendritic cells (DC) is an emerging investigational therapy for eradication of minimal residual disease in acute myeloid leukemia. Various strategies are being explored in manufacturing DC vaccines ex vivo, e.g., monocyte-derived DC (MoDC) loaded with leukemia-associated...

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Detalles Bibliográficos
Autores principales: van den Ancker, Willemijn, van Luijn, Marvin M., Ruben, Jurjen M., Westers, Theresia M., Bontkes, Hetty J., Ossenkoppele, Gert J., de Gruijl, Tanja D., van de Loosdrecht, Arjan A.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029806/
https://www.ncbi.nlm.nih.gov/pubmed/20859626
http://dx.doi.org/10.1007/s00262-010-0917-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029806/
https://www.ncbi.nlm.nih.gov/pubmed/20859626
http://dx.doi.org/10.1007/s00262-010-0917-y

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