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Control of the specificity of T cell-mediated anti-idiotype immunity by natural regulatory T cells
The idiotypes of B cell lymphomas represent tumor-specific antigens. T cell responses induced by idiotype vaccination in vivo are directed predominantly against CDR peptides, whereas in vitro T cells also recognize framework-derived epitopes. To investigate the mechanisms regulating the specificity...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029831/ https://www.ncbi.nlm.nih.gov/pubmed/20848095 http://dx.doi.org/10.1007/s00262-010-0918-x |