MyD88-adaptor protein acts as a preventive mechanism for memory deficits in a mouse model of Alzheimer's disease

BACKGROUND: Alzheimer's disease (AD) is an age-related neurodegenerative disorder associated with brain innate immune activation mainly mediated by microglia. These cells are known to be activated in the brain of AD patients and to produce inflammatory cytokines and neurotoxic molecules in resp...

Descripción completa

Detalles Bibliográficos
Autores principales: Michaud, Jean-Philippe, Richard, Karine L, Rivest, Serge
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030527/
https://www.ncbi.nlm.nih.gov/pubmed/21235801
http://dx.doi.org/10.1186/1750-1326-6-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030527/
https://www.ncbi.nlm.nih.gov/pubmed/21235801
http://dx.doi.org/10.1186/1750-1326-6-5

Ejemplares similares