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Genome-Wide Analysis of Transcriptional Reprogramming in Mouse Models of Acute Myeloid Leukaemia

Acute leukaemias are commonly caused by mutations that corrupt the transcriptional circuitry of haematopoietic stem/progenitor cells. However, the mechanisms underlying large-scale transcriptional reprogramming remain largely unknown. Here we investigated transcriptional reprogramming at genome-scal...

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Detalles Bibliográficos
Autores principales: Bonadies, Nicolas, Foster, Samuel D., Chan, Wai-In, Kvinlaug, Brynn T., Spensberger, Dominik, Dawson, Mark A., Spooncer, Elaine, Whetton, Anthony D., Bannister, Andrew J., Huntly, Brian J., Göttgens, Berthold
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030562/
https://www.ncbi.nlm.nih.gov/pubmed/21297973
http://dx.doi.org/10.1371/journal.pone.0016330