Abnormal Kinetochore-Generated Pulling Forces from Expressing a N-Terminally Modified Hec1

BACKGROUND: Highly Expressed in Cancer protein 1 (Hec1) is a constituent of the Ndc80 complex, a kinetochore component that has been shown to have a fundamental role in stable kinetochore-microtubule attachment, chromosome alignment and spindle checkpoint activation at mitosis. HEC1 RNA is found up-...

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Detalles Bibliográficos
Autores principales: Mattiuzzo, Marta, Vargiu, Giulia, Totta, Pierangela, Fiore, Mario, Ciferri, Claudio, Musacchio, Andrea, Degrassi, Francesca
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030568/
https://www.ncbi.nlm.nih.gov/pubmed/21297979
http://dx.doi.org/10.1371/journal.pone.0016307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030568/
https://www.ncbi.nlm.nih.gov/pubmed/21297979
http://dx.doi.org/10.1371/journal.pone.0016307

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