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Abnormal Kinetochore-Generated Pulling Forces from Expressing a N-Terminally Modified Hec1
BACKGROUND: Highly Expressed in Cancer protein 1 (Hec1) is a constituent of the Ndc80 complex, a kinetochore component that has been shown to have a fundamental role in stable kinetochore-microtubule attachment, chromosome alignment and spindle checkpoint activation at mitosis. HEC1 RNA is found up-...
Autores principales: | Mattiuzzo, Marta, Vargiu, Giulia, Totta, Pierangela, Fiore, Mario, Ciferri, Claudio, Musacchio, Andrea, Degrassi, Francesca |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030568/ https://www.ncbi.nlm.nih.gov/pubmed/21297979 http://dx.doi.org/10.1371/journal.pone.0016307 |
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