Profiling the HER3/PI3K Pathway in Breast Tumors Using Proximity-Directed Assays Identifies Correlations between Protein Complexes and Phosphoproteins

BACKGROUND: The identification of patients for targeted antineoplastic therapies requires accurate measurement of therapeutic targets and associated signaling complexes. HER3 signaling through heterodimerization is an important growth-promoting mechanism in several tumor types and may be a principal...

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Detalles Bibliográficos
Autores principales: Mukherjee, Ali, Badal, Youssouf, Nguyen, Xuan-Thao, Miller, Johanna, Chenna, Ahmed, Tahir, Hasan, Newton, Alicia, Parry, Gordon, Williams, Stephen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030586/
https://www.ncbi.nlm.nih.gov/pubmed/21297994
http://dx.doi.org/10.1371/journal.pone.0016443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030586/
https://www.ncbi.nlm.nih.gov/pubmed/21297994
http://dx.doi.org/10.1371/journal.pone.0016443

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