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Using HSV-TK/GCV suicide gene therapy to inhibit lens epithelial cell proliferation for treatment of posterior capsular opacification

PURPOSE: To establish a novel, targeted lentivirus-based HSV-tk (herpes simplex virus thymidine kinase)/GCV (ganciclovir) gene therapy system to inhibit lens epithelial cell proliferation for treatment of posterior capsular opacification (PCO) after cataract surgery. METHODS: An enhanced Cre recombi...

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Detalles Bibliográficos
Autores principales: Jiang, Yong-Xiang, Lu, Yi, Liu, Tian-Jing, Yang, Jin, Chen, Yan, Fang, Yan-Wen
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030606/
https://www.ncbi.nlm.nih.gov/pubmed/21283526