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Comprehensive Genotyping in Two Homogeneous Graves' Disease Samples Reveals Major and Novel HLA Association Alleles

BACKGROUND: Graves' disease (GD) is the leading cause of hyperthyroidism and thyroid eye disease inherited as a complex trait. Although geoepidemiology studies showed relatively higher prevalence of GD in Asians than in Caucasians, previous genetic studies were contradictory concerning whether...

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Detalles Bibliográficos
Autores principales: Chen, Pei-Lung, Fann, Cathy Shen-Jang, Chu, Chen-Chung, Chang, Chien-Ching, Chang, Su-Wei, Hsieh, Hsin-Yi, Lin, Marie, Yang, Wei-Shiung, Chang, Tien-Chun
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030609/
https://www.ncbi.nlm.nih.gov/pubmed/21307958
http://dx.doi.org/10.1371/journal.pone.0016635