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PD-1 modulates Regulatory T cells and suppresses T cell responses in HCV-associated Lymphoma

T regulatory (T(R)) cells suppress T cell responses that are critical in the development of chronic viral infection and associated malignancies. Programmed death-1 (PD-1) also plays a pivotal role in regulation of T cell functions during chronic viral infection. To examine the role of PD-1 pathway i...

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Detalles Bibliográficos
Autores principales: Ni, Lei, Ma, Cheng J., Zhang, Ying, Nandakumar, Subhadra, Zhang, Chun L., Wu, Xiao Y., Borthwick, Thomas, Hamati, Agnes, Chen, Xin Y., Kumaraguru, Uday, Moorman, Jonathan P., Yao, Zhi Q.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030699/
https://www.ncbi.nlm.nih.gov/pubmed/20975732
http://dx.doi.org/10.1038/icb.2010.121