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Zoledronic acid directly suppresses cell proliferation and induces apoptosis in highly tumorigenic prostate and breast cancers

BACKGROUND: Bisphosphonates (BPs) were designed for the prevention of skeletal-related events secondary to bone metastases. The purpose of this study was to show that zoledronic acid (ZA) directly eradicates highly tumorigenic and potentially metastatic cancer cells. MATERIALS AND METHODS: Human pro...

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Detalles Bibliográficos
Autores principales: Almubarak, Hussain, Jones, Antonia, Chaisuparat, Risa, Zhang, Ming, Meiller, Timothy F., Scheper, Mark A.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030761/
https://www.ncbi.nlm.nih.gov/pubmed/21297922
http://dx.doi.org/10.4103/1477-3163.75723