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Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis

Gene expression profiling has been used previously with spinal cord homogenates and laser capture microdissected motor neurons to determine the mechanisms involved in neurodegeneration in amyotrophic lateral sclerosis. However, while cellular and animal model work has focused on superoxide dismutase...

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Detalles Bibliográficos
Autores principales: Kirby, Janine, Ning, Ke, Ferraiuolo, Laura, Heath, Paul R., Ismail, Azza, Kuo, Su-Wei, Valori, Chiara F., Cox, Laura, Sharrack, Basil, Wharton, Stephen B., Ince, Paul G., Shaw, Pamela J., Azzouz, Mimoun
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030763/
https://www.ncbi.nlm.nih.gov/pubmed/21228060
http://dx.doi.org/10.1093/brain/awq345