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maxAlike: maximum likelihood-based sequence reconstruction with application to improved primer design for unknown sequences

Motivation: The task of reconstructing a genomic sequence from a particular species is gaining more and more importance in the light of the rapid development of high-throughput sequencing technologies and their limitations. Applications include not only compensation for missing data in unsequenced g...

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Detalles Bibliográficos
Autores principales: Menzel, Peter, Stadler, Peter F., Gorodkin, Jan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031029/
https://www.ncbi.nlm.nih.gov/pubmed/21123221
http://dx.doi.org/10.1093/bioinformatics/btq651