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High interferon type I responses in the lung, plasma and spleen during highly pathogenic H5N1 infection of chicken

This study shows that high pathogenic H5N1 influenza virus infection of chicken induced high levels of bioactive interferon type I in the lung (4.3 × 10(5 )U/mg tissue), plasma (1.1 × 10(5 )U/mL), and spleen (9.1 × 10(5 )U/mg tissue). In contrast, a low pathogenic attenuated H5N1 vaccine strain only...

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Detalles Bibliográficos
Autores principales: Moulin, Hervé R, Liniger, Matthias, Python, Sylvie, Guzylack-Piriou, Laurence, Ocaña-Macchi, Manuela, Ruggli, Nicolas, Summerfield, Artur
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031227/
https://www.ncbi.nlm.nih.gov/pubmed/21314963
http://dx.doi.org/10.1186/1297-9716-42-6