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Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis

Individual metastatic tumor cells exhibit two interconvertible modes of cell motility during tissue invasion that are classified as either mesenchymal or amoeboid. The molecular mechanisms by which invasive breast cancer cells regulate this migratory plasticity have yet to be fully elucidated. Herei...

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Detalles Bibliográficos
Autores principales: Deakin, Nicholas O., Turner, Christopher E.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031464/
https://www.ncbi.nlm.nih.gov/pubmed/21148292
http://dx.doi.org/10.1091/mbc.e10-09-0790