Cargando…
Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis
Individual metastatic tumor cells exhibit two interconvertible modes of cell motility during tissue invasion that are classified as either mesenchymal or amoeboid. The molecular mechanisms by which invasive breast cancer cells regulate this migratory plasticity have yet to be fully elucidated. Herei...
Autores principales: | Deakin, Nicholas O., Turner, Christopher E. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031464/ https://www.ncbi.nlm.nih.gov/pubmed/21148292 http://dx.doi.org/10.1091/mbc.e10-09-0790 |
Ejemplares similares
-
Paxillin and Hic-5 Interaction with Vinculin Is Differentially Regulated by Rac1 and RhoA
por: Deakin, Nicholas O., et al.
Publicado: (2012) -
Hic-5 expression is a major indicator of cancer cell morphology, migration, and plasticity in three-dimensional matrices
por: Gulvady, Anushree C., et al.
Publicado: (2018) -
Paxillin inhibits HDAC6 to regulate microtubule acetylation, Golgi structure, and polarized migration
por: Deakin, Nicholas O., et al.
Publicado: (2014) -
Specific Dephosphorylation at Tyr-554 of Git1 by Ptprz Promotes Its Association with Paxillin and Hic-5
por: Fujikawa, Akihiro, et al.
Publicado: (2015) -
LIM Domains Target Actin Regulators Paxillin and Zyxin to Sites of Stress Fiber Strain
por: Smith, Mark A., et al.
Publicado: (2013)