The EDD E3 ubiquitin ligase ubiquitinates and up-regulates β-catenin

Wnt/β-catenin signaling plays a central role in development and is also involved in a diverse array of diseases. β-Catenin activity is tightly regulated via a multiprotein complex that includes the kinase glycogen synthase kinase-3β (GSK-3β). GSK-3β phosphorylates β-catenin, marking it for ubiquitin...

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Detalles Bibliográficos
Autores principales: Hay-Koren, Avital, Caspi, Michal, Zilberberg, Alona, Rosin-Arbesfeld, Rina
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031469/
https://www.ncbi.nlm.nih.gov/pubmed/21118991
http://dx.doi.org/10.1091/mbc.E10-05-0440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031469/
https://www.ncbi.nlm.nih.gov/pubmed/21118991
http://dx.doi.org/10.1091/mbc.E10-05-0440

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