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Regulation of Human Neurotropic JC Virus Replication by Alternative Splicing Factor SF2/ASF in Glial Cells

BACKGROUND: The human neurotropic virus, JC virus (JCV), is the etiologic agent of the fatal demyelinating disease of the central nervous system, Progressive Multifocal Leukoencephlopathy (PML) that is seen primarily in immunodeficient individuals. Productive infection of JCV occurs only in glial ce...

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Detalles Bibliográficos
Autores principales: Sariyer, Ilker Kudret, Khalili, Kamel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031499/
https://www.ncbi.nlm.nih.gov/pubmed/21297941
http://dx.doi.org/10.1371/journal.pone.0014630