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The Actin Binding Domain of βI-Spectrin Regulates the Morphological and Functional Dynamics of Dendritic Spines

Actin microfilaments regulate the size, shape and mobility of dendritic spines and are in turn regulated by actin binding proteins and small GTPases. The βI isoform of spectrin, a protein that links the actin cytoskeleton to membrane proteins, is present in spines. To understand its function, we exp...

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Detalles Bibliográficos
Autores principales: Nestor, Michael W., Cai, Xiang, Stone, Michele R., Bloch, Robert J., Thompson, Scott M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031527/
https://www.ncbi.nlm.nih.gov/pubmed/21297961
http://dx.doi.org/10.1371/journal.pone.0016197