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The Development and Characterization of a Human Mesothelioma In Vitro 3D Model to Investigate Immunotoxin Therapy

BACKGROUND: Tumor microenvironments present significant barriers to penetration by antibodies and immunoconjugates. Tumor microenvironments, however, are difficult to study in vitro. Cells cultured as monolayers exhibit less resistance to therapy than those grown in vivo and an alternative research...

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Detalles Bibliográficos
Autores principales: Xiang, Xinran, Phung, Yen, Feng, Mingqian, Nagashima, Kunio, Zhang, Jingli, Broaddus, V. Courtney, Hassan, Raffit, FitzGerald, David, Ho, Mitchell
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031536/
https://www.ncbi.nlm.nih.gov/pubmed/21305058
http://dx.doi.org/10.1371/journal.pone.0014640