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The Pseudomonas aeruginosa Autoinducer 3O-C12 Homoserine Lactone Provokes Hyperinflammatory Responses from Cystic Fibrosis Airway Epithelial Cells

The discovery of novel antiinflammatory targets to treat inflammation in the cystic fibrosis (CF) lung stands to benefit patient populations suffering with this disease. The Pseudomonas aeruginosa quorum sensing autoinducer N-3-oxododecanoyl homoserine lactone (3O-C12) is an important bacterial viru...

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Detalles Bibliográficos
Autores principales: Mayer, Matthew L., Sheridan, Jared A., Blohmke, Christoph J., Turvey, Stuart E., Hancock, Robert E. W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031552/
https://www.ncbi.nlm.nih.gov/pubmed/21305014
http://dx.doi.org/10.1371/journal.pone.0016246