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Effect of Population Heterogenization on the Reproducibility of Mouse Behavior: A Multi-Laboratory Study

In animal experiments, animals, husbandry and test procedures are traditionally standardized to maximize test sensitivity and minimize animal use, assuming that this will also guarantee reproducibility. However, by reducing within-experiment variation, standardization may limit inference to the spec...

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Detalles Bibliográficos
Autores principales: Richter, S. Helene, Garner, Joseph P., Zipser, Benjamin, Lewejohann, Lars, Sachser, Norbert, Touma, Chadi, Schindler, Britta, Chourbaji, Sabine, Brandwein, Christiane, Gass, Peter, van Stipdonk, Niek, van der Harst, Johanneke, Spruijt, Berry, Võikar, Vootele, Wolfer, David P., Würbel, Hanno
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031565/
https://www.ncbi.nlm.nih.gov/pubmed/21305027
http://dx.doi.org/10.1371/journal.pone.0016461