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Resveratrol Inhibits Pancreatic Cancer Stem Cell Characteristics in Human and Kras(G12D) Transgenic Mice by Inhibiting Pluripotency Maintaining Factors and Epithelial-Mesenchymal Transition

BACKGROUND: Cancer stem cells (CSCs) can proliferate and self-renew extensively due to their ability to express anti-apoptotic and drug resistant proteins, thus sustaining tumor growth. Therefore, the strategy to eradicate CSCs might have significant clinical implications. The objectives of this stu...

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Detalles Bibliográficos
Autores principales: Shankar, Sharmila, Nall, Dara, Tang, Su-Ni, Meeker, Daniel, Passarini, Jenna, Sharma, Jay, Srivastava, Rakesh K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031576/
https://www.ncbi.nlm.nih.gov/pubmed/21304978
http://dx.doi.org/10.1371/journal.pone.0016530