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Resveratrol Inhibits Pancreatic Cancer Stem Cell Characteristics in Human and Kras(G12D) Transgenic Mice by Inhibiting Pluripotency Maintaining Factors and Epithelial-Mesenchymal Transition
BACKGROUND: Cancer stem cells (CSCs) can proliferate and self-renew extensively due to their ability to express anti-apoptotic and drug resistant proteins, thus sustaining tumor growth. Therefore, the strategy to eradicate CSCs might have significant clinical implications. The objectives of this stu...
Autores principales: | Shankar, Sharmila, Nall, Dara, Tang, Su-Ni, Meeker, Daniel, Passarini, Jenna, Sharma, Jay, Srivastava, Rakesh K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031576/ https://www.ncbi.nlm.nih.gov/pubmed/21304978 http://dx.doi.org/10.1371/journal.pone.0016530 |
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