Epistatic Interactions in Genetic Regulation of t-PA and PAI-1 Levels in a Ghanaian Population

The proteins, tissue plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1), act in concert to balance thrombus formation and degradation, thereby modulating the development of arterial thrombosis and excessive bleeding. PAI-1 is upregulated by the renin-angiotensin system (RAS),...

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Detalles Bibliográficos
Autores principales: Penrod, Nadia M., Poku, Kwabena A., Vaughn, Douglas E., Asselbergs, Folkert W., Brown, Nancy J., Moore, Jason H., Williams, Scott M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031598/
https://www.ncbi.nlm.nih.gov/pubmed/21304999
http://dx.doi.org/10.1371/journal.pone.0016639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031598/
https://www.ncbi.nlm.nih.gov/pubmed/21304999
http://dx.doi.org/10.1371/journal.pone.0016639

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