Inaccurate DNA Synthesis in Cell Extracts of Yeast Producing Active Human DNA Polymerase Iota

Mammalian Pol ι has an unusual combination of properties: it is stimulated by Mn(2+) ions, can bypass some DNA lesions and misincorporates “G” opposite template “T” more frequently than incorporates the correct “A.” We recently proposed a method of detection of Pol ι activity in animal cell extracts...

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Detalles Bibliográficos
Autores principales: Makarova, Alena V., Grabow, Corinn, Gening, Leonid V., Tarantul, Vyacheslav Z., Tahirov, Tahir H., Bessho, Tadayoshi, Pavlov, Youri I.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031609/
https://www.ncbi.nlm.nih.gov/pubmed/21304950
http://dx.doi.org/10.1371/journal.pone.0016612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031609/
https://www.ncbi.nlm.nih.gov/pubmed/21304950
http://dx.doi.org/10.1371/journal.pone.0016612

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