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Epistasis between COMT and MTHFR in Maternal-Fetal Dyads Increases Risk for Preeclampsia

Preeclampsia is a leading cause of perinatal morbidity and mortality. This disorder is thought to be multifactorial in origin, with multiple genes, environmental and social factors, contributing to disease. One proposed mechanism is placental hypoxia-driven imbalances in angiogenic and anti-angiogen...

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Detalles Bibliográficos
Autores principales: Hill, Lori D., York, Timothy P., Kusanovic, Juan P., Gomez, Ricardo, Eaves, Lindon J., Romero, Roberto, Strauss, Jerome F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031618/
https://www.ncbi.nlm.nih.gov/pubmed/21304959
http://dx.doi.org/10.1371/journal.pone.0016681