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Epistasis between COMT and MTHFR in Maternal-Fetal Dyads Increases Risk for Preeclampsia
Preeclampsia is a leading cause of perinatal morbidity and mortality. This disorder is thought to be multifactorial in origin, with multiple genes, environmental and social factors, contributing to disease. One proposed mechanism is placental hypoxia-driven imbalances in angiogenic and anti-angiogen...
Autores principales: | Hill, Lori D., York, Timothy P., Kusanovic, Juan P., Gomez, Ricardo, Eaves, Lindon J., Romero, Roberto, Strauss, Jerome F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031618/ https://www.ncbi.nlm.nih.gov/pubmed/21304959 http://dx.doi.org/10.1371/journal.pone.0016681 |
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