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Detection and Removal of Biases in the Analysis of Next-Generation Sequencing Reads
Since the emergence of next-generation sequencing (NGS) technologies, great effort has been put into the development of tools for analysis of the short reads. In parallel, knowledge is increasing regarding biases inherent in these technologies. Here we discuss four different biases we encountered wh...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031631/ https://www.ncbi.nlm.nih.gov/pubmed/21304912 http://dx.doi.org/10.1371/journal.pone.0016685 |