Intra-tumour genetic heterogeneity and poor chemoradiotherapy response in cervical cancer

BACKGROUND: Intra-tumour genetic heterogeneity has been reported in both leukaemias and solid tumours and is implicated in the development of drug resistance in CML and AML. The role of genetic heterogeneity in drug response in solid tumours is unknown. METHODS: To investigate intra-tumour genetic h...

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Detalles Bibliográficos
Autores principales: Cooke, S L, Temple, J, MacArthur, S, Zahra, M A, Tan, L T, Crawford, R A F, Ng, C K Y, Jimenez-Linan, M, Sala, E, Brenton, J D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031882/
https://www.ncbi.nlm.nih.gov/pubmed/21063398
http://dx.doi.org/10.1038/sj.bjc.6605971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031882/
https://www.ncbi.nlm.nih.gov/pubmed/21063398
http://dx.doi.org/10.1038/sj.bjc.6605971

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