The HPV16 E6 binding protein Tip-1 interacts with ARHGEF16, which activates Cdc42

BACKGROUND: Guanidine exchange factor (GEF)-catalysed activation of Rho proteins such as Cdc42 has been shown to have a crucial role in cellular transformation, malignant progression and invasion. We have previously shown that the HPV16 E6 oncoprotein binds to the PDZ domain protein Tax-interacting-...

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Detalles Bibliográficos
Autores principales: Oliver, A W, He, X, Borthwick, K, Donne, A J, Hampson, L, Hampson, I N
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031889/
https://www.ncbi.nlm.nih.gov/pubmed/21139582
http://dx.doi.org/10.1038/sj.bjc.6606026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031889/
https://www.ncbi.nlm.nih.gov/pubmed/21139582
http://dx.doi.org/10.1038/sj.bjc.6606026

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