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The HPV16 E6 binding protein Tip-1 interacts with ARHGEF16, which activates Cdc42
BACKGROUND: Guanidine exchange factor (GEF)-catalysed activation of Rho proteins such as Cdc42 has been shown to have a crucial role in cellular transformation, malignant progression and invasion. We have previously shown that the HPV16 E6 oncoprotein binds to the PDZ domain protein Tax-interacting-...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031889/ https://www.ncbi.nlm.nih.gov/pubmed/21139582 http://dx.doi.org/10.1038/sj.bjc.6606026 |