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Structural Characterization of Partially Disordered Human Chibby: Insights into Its Function in the Wnt-Signaling Pathway

[Image: see text] The Wnt/β-catenin signaling pathway is critical to embryonic development as well as adult tissue regeneration. Dysregulation of this pathway can lead to a variety of human diseases, in particular cancers. Chibby (Cby), a small and highly conserved protein, plays an antagonistic rol...

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Detalles Bibliográficos
Autores principales: Mokhtarzada, Sulayman, Yu, Corey, Brickenden, Anne, Choy, Wing-Yiu
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031990/
https://www.ncbi.nlm.nih.gov/pubmed/21182262
http://dx.doi.org/10.1021/bi101236z