Transient expression of OCT4 is sufficient to allow human keratinocytes to change their differentiation pathway

Here, we describe a simple system in which human keratinocytes can be redirected to an alternative differentiation pathway. We transiently transfected freshly isolated human skin keratinocytes with the single transcription factor OCT4. Within two days these cells displayed expression of endogenous e...

Descripción completa

Detalles Bibliográficos
Autores principales: Racila, Doina, Winter, Michael, Said, Mohammed, Tomanek-Chalkley, Ann, Wiechert, Susan, Eckert, Richard L., Bickenbach, Jackie R.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032017/
https://www.ncbi.nlm.nih.gov/pubmed/20981110
http://dx.doi.org/10.1038/gt.2010.148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032017/
https://www.ncbi.nlm.nih.gov/pubmed/20981110
http://dx.doi.org/10.1038/gt.2010.148

Ejemplares similares