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Tropheryma whipplei, the Whipple's disease bacillus, induces macrophage apoptosis through the extrinsic pathway

Tropheryma whipplei, the etiological agent of Whipple's disease, is an intracellular bacterium that infects macrophages. We previously showed that infection of macrophages results in M2 polarization associated with induction of apoptosis and interleukin (IL)-16 secretion. In patients with Whipp...

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Detalles Bibliográficos
Autores principales: Gorvel, L, Al Moussawi, K, Ghigo, E, Capo, C, Mege, J-L, Desnues, B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032299/
https://www.ncbi.nlm.nih.gov/pubmed/21364641
http://dx.doi.org/10.1038/cddis.2010.11