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CXCL12 inhibits expression of the NMDA receptor's NR2B subunit through a histone deacetylase-dependent pathway contributing to neuronal survival

Homeostatic chemokines, such as CXCL12, can affect neuronal activity by the regulation of inhibitory and excitatory neurotransmission, but the mechanisms involved are still undefined. Our previous studies have shown that CXCL12 protects cortical neurons from excitotoxicity by promoting the function...

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Detalles Bibliográficos
Autores principales: Nicolai, J, Burbassi, S, Rubin, J, Meucci, O
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032300/
https://www.ncbi.nlm.nih.gov/pubmed/21364640
http://dx.doi.org/10.1038/cddis.2010.10