p53-mediated delayed NF-κB activity enhances etoposide-induced cell death in medulloblastoma

Medulloblastoma (MB) is an embryonic brain tumour that arises in the cerebellum. Using several MB cell lines, we have demonstrated that the chemotherapeutic drug etoposide induces a p53- and caspase-dependent cell death. We have observed an additional caspase-independent cell death mechanism involvi...

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Detalles Bibliográficos
Autores principales: Meley, D, Spiller, D G, White, M R H, McDowell, H, Pizer, B, Sée, V
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032310/
https://www.ncbi.nlm.nih.gov/pubmed/21364648
http://dx.doi.org/10.1038/cddis.2010.16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032310/
https://www.ncbi.nlm.nih.gov/pubmed/21364648
http://dx.doi.org/10.1038/cddis.2010.16

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