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p53-mediated delayed NF-κB activity enhances etoposide-induced cell death in medulloblastoma
Medulloblastoma (MB) is an embryonic brain tumour that arises in the cerebellum. Using several MB cell lines, we have demonstrated that the chemotherapeutic drug etoposide induces a p53- and caspase-dependent cell death. We have observed an additional caspase-independent cell death mechanism involvi...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032310/ https://www.ncbi.nlm.nih.gov/pubmed/21364648 http://dx.doi.org/10.1038/cddis.2010.16 |