Pro-apoptotic Bax is the major and Bak an auxiliary effector in cytokine deprivation-induced mast cell apoptosis

The process of apoptosis in immune cells like mast cells is essential to regain homeostasis after an inflammatory response. The intrinsic pathway of apoptosis is ultimately controlled by the pro-apoptotic Bcl-2 family members Bax and Bak, which upon activation oligomerize to cause increased permeabi...

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Detalles Bibliográficos
Autores principales: Karlberg, M, Ekoff, M, Labi, V, Strasser, A, Huang, D, Nilsson, G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032311/
https://www.ncbi.nlm.nih.gov/pubmed/21364649
http://dx.doi.org/10.1038/cddis.2010.20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032311/
https://www.ncbi.nlm.nih.gov/pubmed/21364649
http://dx.doi.org/10.1038/cddis.2010.20

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