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Bcl-2-regulated cell death signalling in the prevention of autoimmunity

Cell death mediated through the intrinsic, Bcl-2-regulated mitochondrial apoptosis signalling pathway is critical for lymphocyte development and the establishment of central and maintenance of peripheral tolerance. Defects in Bcl-2-regulated cell death signalling have been reported to cause or corre...

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Detalles Bibliográficos
Autores principales: Tischner, D, Woess, C, Ottina, E, Villunger, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032315/
https://www.ncbi.nlm.nih.gov/pubmed/21364654
http://dx.doi.org/10.1038/cddis.2010.27