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CLIMP-63 is a gentamicin-binding protein that is involved in drug-induced cytotoxicity
Aminoglycoside-induced nephrotoxicity and ototoxicity is a major clinical problem. To understand how aminoglycosides, including gentamicin, induce cytotoxicity in the kidney proximal tubule and the inner ear, we identified gentamicin-binding proteins (GBPs) from mouse kidney cells by pulling down GB...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032319/ https://www.ncbi.nlm.nih.gov/pubmed/21368867 http://dx.doi.org/10.1038/cddis.2010.80 |