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Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse

Inherited retinal degenerations, collectively termed retinitis pigmentosa (RP), constitute one of the leading causes of blindness in the developed world. RP is at present untreatable and the underlying neurodegenerative mechanisms are unknown, even though the genetic causes are often established. Ac...

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Detalles Bibliográficos
Autores principales: Sancho-Pelluz, J, Alavi, M V, Sahaboglu, A, Kustermann, S, Farinelli, P, Azadi, S, van Veen, T, Romero, F J, Paquet-Durand, F, Ekström, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032332/
https://www.ncbi.nlm.nih.gov/pubmed/21364632
http://dx.doi.org/10.1038/cddis.2010.4