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Cathepsin B-like and cell death in the unicellular human pathogen Leishmania

In several studies reporting cell death (CD) in lower eukaryotes and in the human protozoan parasite Leishmania, proteolytic activity was revealed using pan-caspase substrates or inhibitors such as carbobenzoxy-valyl-alanyl-aspartyl-[O-methyl]-fluoromethylketone (Z-VAD-FMK). However, most of the low...

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Detalles Bibliográficos
Autores principales: El-Fadili, A K, Zangger, H, Desponds, C, Gonzalez, I J, Zalila, H, Schaff, C, Ives, A, Masina, S, Mottram, J C, Fasel, N
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032344/
https://www.ncbi.nlm.nih.gov/pubmed/21364675
http://dx.doi.org/10.1038/cddis.2010.51