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Deficient incorporation of spike protein into virions contributes to the lack of infectivity following establishment of a persistent, non-productive infection in oligodendroglial cell culture by murine coronavirus

Infection of mouse oligodendrocytes with a recombinant mouse hepatitis virus (MHV) expressing a green fluorescence protein facilitated specific selection of virus-infected cells and subsequent establishment of persistence. Interestingly, while viral genomic RNAs persisted in infected cells over 14 s...

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Detalles Bibliográficos
Autores principales: Liu, Yin, Herbst, Werner, Cao, Jianzhong, Zhang, Xuming
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032362/
https://www.ncbi.nlm.nih.gov/pubmed/21035161
http://dx.doi.org/10.1016/j.virol.2010.10.006