Cargando…

Mutant Huntingtin induces activation of the Bcl-2/adenovirus E1B 19-kDa interacting protein (BNip3)

Huntington's disease (HD) is a neurodegenerative disorder characterized by progressive neuronal death in the basal ganglia and cortex. Although increasing evidence supports a pivotal role of mitochondrial dysfunction in the death of patients' neurons, the molecular bases for mitochondrial...

Descripción completa

Detalles Bibliográficos
Autores principales: Sassone, J, Colciago, C, Marchi, P, Ascardi, C, Alberti, L, Di Pardo, A, Zippel, R, Sipione, S, Silani, V, Ciammola, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032515/
https://www.ncbi.nlm.nih.gov/pubmed/21364626
http://dx.doi.org/10.1038/cddis.2009.6