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Partial dysferlin reconstitution by adult murine mesoangioblasts is sufficient for full functional recovery in a murine model of dysferlinopathy

Dysferlin deficiency leads to a peculiar form of muscular dystrophy due to a defect in sarcolemma repair and currently lacks a therapy. We developed a cell therapy protocol with wild-type adult murine mesoangioblasts. These cells differentiate with high efficiency into skeletal muscle in vitro but d...

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Detalles Bibliográficos
Autores principales: Díaz-Manera, J, Touvier, T, Dellavalle, A, Tonlorenzi, R, Tedesco, F S, Messina, G, Meregalli, M, Navarro, C, Perani, L, Bonfanti, C, Illa, I, Torrente, Y, Cossu, G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032521/
https://www.ncbi.nlm.nih.gov/pubmed/21364666
http://dx.doi.org/10.1038/cddis.2010.35