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Inhibition of TXNIP expression in vivo blocks early pathologies of diabetic retinopathy

Evidence is mounting that proinflammatory and proapoptotic thioredoxin-interacting protein (TXNIP) has a causative role in the development of diabetes. However, there are no studies investigating the role of TXNIP in diabetic retinopathy (DR). Here, we show that, in diabetic rats, TXNIP expression a...

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Detalles Bibliográficos
Autores principales: Perrone, L, Devi, T S, Hosoya, K-I, Terasaki, T, Singh, L P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032527/
https://www.ncbi.nlm.nih.gov/pubmed/21364670
http://dx.doi.org/10.1038/cddis.2010.42