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Survivin withdrawal by nuclear export failure as a physiological switch to commit cells to apoptosis

Apoptosis is a tightly controlled process regulated by many signaling pathways; however, the mechanisms and cellular events that decide whether a cell lives or dies remain poorly understood. Here we showed that when a cell is under apoptotic stress, the prosurvival protein Survivin redistributes fro...

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Detalles Bibliográficos
Autores principales: Chan, K-S, Wong, C-H, Huang, Y-F, Li, H-Y
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032555/
https://www.ncbi.nlm.nih.gov/pubmed/21364662
http://dx.doi.org/10.1038/cddis.2010.34