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Survivin withdrawal by nuclear export failure as a physiological switch to commit cells to apoptosis
Apoptosis is a tightly controlled process regulated by many signaling pathways; however, the mechanisms and cellular events that decide whether a cell lives or dies remain poorly understood. Here we showed that when a cell is under apoptotic stress, the prosurvival protein Survivin redistributes fro...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032555/ https://www.ncbi.nlm.nih.gov/pubmed/21364662 http://dx.doi.org/10.1038/cddis.2010.34 |